Course of acute nonspecific mesenteric lymphadenitis: single-center experience

Cecilia Benetti, Elisa Conficconi, Flurim Hamitaga, Marina Wyttenbach, Sebastiano A.G. Lava, Gregorio P. Milani, Mario G. Bianchetti, Giacomo D. Simonetti, Rossana Helbling

Research output: Contribution to journalArticlepeer-review


Available reports dealing with acute nonspecific mesenteric lymphadenitis do not address the total duration of symptoms. However, it is commonly assumed a time for recovery ≤ 4 weeks. The purpose of this report was to investigate the course of acute nonspecific mesenteric lymphadenitis in childhood. A review was made of the patients aged ≤ 16 years in whom the diagnosis of acute nonspecific mesenteric lymphadenitis was established between 2011 and 2015 at the Pediatric Emergency Unit. The records of the Pediatric Emergency Unit, those of the referring family doctors, and the results of a structured telephone interview with each family were used. Forty-four patients (25 girls and 19 boys) aged 2.5 to 16, median 8.2, years were included. A bimodal distribution in duration of symptoms was observed: symptoms persisted for ≤ 2 weeks in 22 patients and 3 to 10 weeks in 22. Clinical and laboratory characteristics were similar in children with symptoms persisting for 2 weeks or less 28 and in those with symptoms persisting for 3–10 weeks. Conclusion: In patients affected with acute nonspecific mesenteric lymphadenitis, it is advantageous to think of the time span for recovery in terms of ≥ 4 weeks.(Table presented.)

Original languageEnglish
Pages (from-to)243-246
Number of pages4
JournalEuropean Journal of Pediatrics
Issue number2
Publication statusPublished - 2018


  • Abdominal pain
  • Appendicitis
  • Lymphadenopathy
  • Mesenteric lymph nodes
  • Ultrasonography

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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