TY - JOUR
T1 - Correlation between atopy and hypersensitivity reactions during therapy with three different TNF-cL blocking agents in rheumatoid arthritis
AU - Benucci, M.
AU - Manfredi, M.
AU - Saviola, G.
AU - Baiardi, P.
AU - Campi, P.
PY - 2009/3
Y1 - 2009/3
N2 - The use of TNF-a antagonists (infliximab, etanercept, adalimumab) has changed the course of many rheumatic diseases including rheumatoid arthritis (RA). Since their approval, some questions regarding their safety have been raised. Both acute and delayed reactions have been described. Methods. The aim of our work was to detect if there is a different incidence of hypersensitivity reactions infusion reactions to infliximab or injection site reactions with etanercept or adalimumab in atopic patients versus nonatopic patients. In 90 patients (82 females, 8 males) with rheumatoid arthritis we evaluated, during the first year of therapy with three different TNF-α blocking agents, total serum IgE (normal value
AB - The use of TNF-a antagonists (infliximab, etanercept, adalimumab) has changed the course of many rheumatic diseases including rheumatoid arthritis (RA). Since their approval, some questions regarding their safety have been raised. Both acute and delayed reactions have been described. Methods. The aim of our work was to detect if there is a different incidence of hypersensitivity reactions infusion reactions to infliximab or injection site reactions with etanercept or adalimumab in atopic patients versus nonatopic patients. In 90 patients (82 females, 8 males) with rheumatoid arthritis we evaluated, during the first year of therapy with three different TNF-α blocking agents, total serum IgE (normal value
KW - Anti-TNF alpha
KW - Atopy
KW - Hypersensitivity reactions
UR - http://www.scopus.com/inward/record.url?scp=67249097204&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67249097204&partnerID=8YFLogxK
M3 - Article
C2 - 19473578
AN - SCOPUS:67249097204
SN - 0392-856X
VL - 27
SP - 333
EP - 336
JO - Clinical and Experimental Rheumatology
JF - Clinical and Experimental Rheumatology
IS - 2
ER -