Construction of a YAC contig covering human chromosome 6p22

Patrizia Malaspina; Antonella Roetto; Flavia Trettel; Carla Jodice; Paola Blasi; Marina Frontali; Massimo Carella; Brunella Franco; Clara Camaschella; Andrea Novelletto

doi:10.1006/geno.1996.0484

Construction of a YAC contig covering human chromosome 6p22

Patrizia Malaspina, Antonella Roetto, Flavia Trettel, Carla Jodice, Paola Blasi, Marina Frontali, Massimo Carella, Brunella Franco, Clara Camaschella, Andrea Novelletto

Research output: Contribution to journal › Article › peer-review

Abstract

A contig covering human chromosome 6p22 that consists of 134 YAC clones aligned based on the presence/absence of 52 DNA markers is presented. This contig overlaps with the 6p23 contig at its telomeric end and with the 6p21.3 contig at its centromeric end. The order of loci within the contig resolves the relative positions of several genetically mapped markers. Among the additional markers used here, there are eight novel PCR assays. The 12 known genes and anonymous ESTs located within the contig establish a first step toward a transcriptional map of this region. The instability of YAC clones observed during this work is also discussed.

Original language	English
Pages (from-to)	399-407
Number of pages	9
Journal	Genomics
Volume	36
Issue number	3
DOIs	https://doi.org/10.1006/geno.1996.0484
Publication status	Published - Sept 15 1996

ASJC Scopus subject areas

Genetics

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10.1006/geno.1996.0484

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title = "Construction of a YAC contig covering human chromosome 6p22",

abstract = "A contig covering human chromosome 6p22 that consists of 134 YAC clones aligned based on the presence/absence of 52 DNA markers is presented. This contig overlaps with the 6p23 contig at its telomeric end and with the 6p21.3 contig at its centromeric end. The order of loci within the contig resolves the relative positions of several genetically mapped markers. Among the additional markers used here, there are eight novel PCR assays. The 12 known genes and anonymous ESTs located within the contig establish a first step toward a transcriptional map of this region. The instability of YAC clones observed during this work is also discussed.",

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AU - Malaspina, Patrizia

AU - Roetto, Antonella

AU - Trettel, Flavia

AU - Jodice, Carla

AU - Blasi, Paola

AU - Frontali, Marina

AU - Carella, Massimo

AU - Franco, Brunella

AU - Camaschella, Clara

AU - Novelletto, Andrea

PY - 1996/9/15

Y1 - 1996/9/15

N2 - A contig covering human chromosome 6p22 that consists of 134 YAC clones aligned based on the presence/absence of 52 DNA markers is presented. This contig overlaps with the 6p23 contig at its telomeric end and with the 6p21.3 contig at its centromeric end. The order of loci within the contig resolves the relative positions of several genetically mapped markers. Among the additional markers used here, there are eight novel PCR assays. The 12 known genes and anonymous ESTs located within the contig establish a first step toward a transcriptional map of this region. The instability of YAC clones observed during this work is also discussed.

AB - A contig covering human chromosome 6p22 that consists of 134 YAC clones aligned based on the presence/absence of 52 DNA markers is presented. This contig overlaps with the 6p23 contig at its telomeric end and with the 6p21.3 contig at its centromeric end. The order of loci within the contig resolves the relative positions of several genetically mapped markers. Among the additional markers used here, there are eight novel PCR assays. The 12 known genes and anonymous ESTs located within the contig establish a first step toward a transcriptional map of this region. The instability of YAC clones observed during this work is also discussed.

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Construction of a YAC contig covering human chromosome 6p22

Abstract

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