TY - JOUR
T1 - Consensus five factor PANSS for evaluation of clinical remission
T2 - Effects on functioning and cognitive performances
AU - Pinna, Federica
AU - Bosia, Marta
AU - Cavallaro, Roberto
AU - Carpiniello, Bernardo
PY - 2014
Y1 - 2014
N2 - Criteria developed by the Remission in Schizophrenia Working Group (RSWG), based upon 8 core symptoms of PANSS, are generally used for evaluation of Remission. However, some concerns have arisen as regard to the ability of the RSWG criteria to detect truly remitted cases. This study aims to compare the severity criteria of remission defined by the RSWG (RSWG-cr) with more restrictive criteria, based upon the use of PANSS factor model. Methods: 112 chronic psychotic outpatients were examined. Symptomatic remission according to RSWGcr was compared with remission according to criteria based on the 20-items of PANSS considered in the consensus five factor model (PANSS-FCTcr), in relation to functional and neurocognitive outcomes. Results: Data from the study demonstrated the superiority of PANSS-FCTcr in identifying patients with higher functional and cognitive outcomes. Conclusion: PANSS-FCTcr seems to be suitable for use in both common clinical practice and research setting, being associated with improved identification of truly remitted patients.
AB - Criteria developed by the Remission in Schizophrenia Working Group (RSWG), based upon 8 core symptoms of PANSS, are generally used for evaluation of Remission. However, some concerns have arisen as regard to the ability of the RSWG criteria to detect truly remitted cases. This study aims to compare the severity criteria of remission defined by the RSWG (RSWG-cr) with more restrictive criteria, based upon the use of PANSS factor model. Methods: 112 chronic psychotic outpatients were examined. Symptomatic remission according to RSWGcr was compared with remission according to criteria based on the 20-items of PANSS considered in the consensus five factor model (PANSS-FCTcr), in relation to functional and neurocognitive outcomes. Results: Data from the study demonstrated the superiority of PANSS-FCTcr in identifying patients with higher functional and cognitive outcomes. Conclusion: PANSS-FCTcr seems to be suitable for use in both common clinical practice and research setting, being associated with improved identification of truly remitted patients.
KW - Cognition
KW - Functioning
KW - PANSS factors
KW - Remission
KW - Schizophrenia
UR - http://www.scopus.com/inward/record.url?scp=84926147961&partnerID=8YFLogxK
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U2 - 10.1016/j.scog.2014.11.001
DO - 10.1016/j.scog.2014.11.001
M3 - Article
AN - SCOPUS:84926147961
SN - 2215-0013
VL - 1
SP - 187
EP - 192
JO - Schizophrenia Research: Cognition
JF - Schizophrenia Research: Cognition
IS - 4
ER -