Complications and outcomes of SARS-CoV-2 in pregnancy: where and what is the evidence?

Ayssa Teles Abrao Trad, Eniola R Ibirogba, Amro Elrefaei, Kavita Narang, Gabriele Tonni, Olivier Picone, Anna Suy, Elena Carreras Moratonas, Mark D Kilby, Rodrigo Ruano

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVES: To add to the growing evidence on SARS-CoV-2 infection during pregnancy, so as to better inform clinical decision making and optimize patient outcomes.

METHODS: A systematic search of relevant databases was perfomed on 25 March 2020 and a repeat search, on 10 April 2020. Reports of pregnant patients with SARS-CoV-2 infection at any time during their pregnancy were reviewed and summarized .

RESULTS: We summarized the outcomes of a total of 155 pregnant women and 118 neonates. The evidence suggests a similar rate of severe COVID-19 cases in pregnant women and the general population. The frequency of cesarean deliveries is high, against guidelines recommendations.

CONCLUSION: Limited data on COVID-19 during preganacy, associated with a wide variation in the methodology make accurate data interpretation difficult.

Original languageEnglish
Pages (from-to)361-369
Number of pages9
JournalHypertension in Pregnancy
Volume39
Issue number3
DOIs
Publication statusPublished - Aug 2020
Externally publishedYes

Keywords

  • Betacoronavirus
  • COVID-19
  • Cesarean Section/statistics & numerical data
  • Coronavirus Infections/complications
  • Female
  • Humans
  • Pandemics
  • Pneumonia, Viral/complications
  • Pregnancy
  • Pregnancy Complications, Infectious/diagnosis
  • Prognosis
  • SARS-CoV-2
  • Severity of Illness Index

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