TY - JOUR
T1 - Comparison of different positron emission tomography tracers in patients with recurrent medullary thyroid carcinoma
T2 - Our experience and a review of the literature
AU - Treglia, Giorgio
AU - Castaldi, Paola
AU - Villani, Maria Felicia
AU - Perotti, Germano
AU - Filice, Angelina
AU - Ambrosini, Valentina
AU - Cremonini, Nadia
AU - Versari, Annibale
AU - Fanti, Stefano
AU - Giordano, Alessandro
AU - Rufini, Vittoria
PY - 2013
Y1 - 2013
N2 - Several morphological and functional imaging techniques are usually used to detect residual/recurrent medullary thyroid carcinoma (MTC) with variable results; currently, there is growing interest in positron emission tomography (PET) methodology. Herein, we report our experience of and a literature review about the comparison of different positron emission tomography (PET) tracers in patients with residual/recurrent MTC. 18F-DOPA PET/CT seems to be the most useful imaging method to detect recurrent MTC lesions, performing better than 18F-FDG and 68Ga-somatostatin analogs PET/CT. 18F-FDG may complement 18F-DOPA in patients with aggressive tumors. 68Ga-somatostatin analogs PET/CT may be useful to select patients who could benefit from radioreceptor therapy. The information provided by the various PET tracers reflects different metabolic pathways, and may help to select the most appropriate treatment.
AB - Several morphological and functional imaging techniques are usually used to detect residual/recurrent medullary thyroid carcinoma (MTC) with variable results; currently, there is growing interest in positron emission tomography (PET) methodology. Herein, we report our experience of and a literature review about the comparison of different positron emission tomography (PET) tracers in patients with residual/recurrent MTC. 18F-DOPA PET/CT seems to be the most useful imaging method to detect recurrent MTC lesions, performing better than 18F-FDG and 68Ga-somatostatin analogs PET/CT. 18F-FDG may complement 18F-DOPA in patients with aggressive tumors. 68Ga-somatostatin analogs PET/CT may be useful to select patients who could benefit from radioreceptor therapy. The information provided by the various PET tracers reflects different metabolic pathways, and may help to select the most appropriate treatment.
KW - Diagnosis
KW - Medullary thyroid carcinoma
KW - Neuroendocrine tumors
KW - PET/CT
KW - Positron emission tomography
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U2 - 10.1007/978-3-642-27994-2-21
DO - 10.1007/978-3-642-27994-2-21
M3 - Article
C2 - 22918771
AN - SCOPUS:84867049958
SN - 0080-0015
VL - 194
SP - 385
EP - 393
JO - Recent Results in Cancer Research
JF - Recent Results in Cancer Research
ER -