Coexistence of substance P and calcitonin gene-related peptide in the frog spinal cord

Tiziana Venesio; Bruno Mulatero; Aldo Fasolo

doi:10.1016/0304-3940(87)90462-9

Coexistence of substance P and calcitonin gene-related peptide in the frog spinal cord

Tiziana Venesio, Bruno Mulatero, Aldo Fasolo

Istituto Oncologico Candiolo

Research output: Contribution to journal › Article › peer-review

Abstract

The localization of substance P (SP) and calcitonin gene-related peptide (CGRP) was studied in the untreated spinal cord of the frog using single or double immunohistochemical stainings. SP and CGRP appear to coexist in the primary afferent fibers and in the marginal and submarginal dorsal horn zones, as well as in the dorsolateral zone. In other parts of the spinal cord CGRP immunoreactivity was scanty while diffuse SP systems were seen, suggesting that the coexistence of the two peptides is restricted to primary afferent fibers.

Original language	English
Pages (from-to)	246-250
Number of pages	5
Journal	Neuroscience Letters
Volume	80
Issue number	3
DOIs	https://doi.org/10.1016/0304-3940(87)90462-9
Publication status	Published - Oct 5 1987

Keywords

Calcitonin gene-related peptide
Coexistence
Double method
Frog
Immunohistochemistry
Spinal cord
Substance P

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/0304-3940(87)90462-9

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title = "Coexistence of substance P and calcitonin gene-related peptide in the frog spinal cord",

abstract = "The localization of substance P (SP) and calcitonin gene-related peptide (CGRP) was studied in the untreated spinal cord of the frog using single or double immunohistochemical stainings. SP and CGRP appear to coexist in the primary afferent fibers and in the marginal and submarginal dorsal horn zones, as well as in the dorsolateral zone. In other parts of the spinal cord CGRP immunoreactivity was scanty while diffuse SP systems were seen, suggesting that the coexistence of the two peptides is restricted to primary afferent fibers.",

keywords = "Calcitonin gene-related peptide, Coexistence, Double method, Frog, Immunohistochemistry, Spinal cord, Substance P",

author = "Tiziana Venesio and Bruno Mulatero and Aldo Fasolo",

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T1 - Coexistence of substance P and calcitonin gene-related peptide in the frog spinal cord

AU - Venesio, Tiziana

AU - Mulatero, Bruno

AU - Fasolo, Aldo

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Y1 - 1987/10/5

N2 - The localization of substance P (SP) and calcitonin gene-related peptide (CGRP) was studied in the untreated spinal cord of the frog using single or double immunohistochemical stainings. SP and CGRP appear to coexist in the primary afferent fibers and in the marginal and submarginal dorsal horn zones, as well as in the dorsolateral zone. In other parts of the spinal cord CGRP immunoreactivity was scanty while diffuse SP systems were seen, suggesting that the coexistence of the two peptides is restricted to primary afferent fibers.

AB - The localization of substance P (SP) and calcitonin gene-related peptide (CGRP) was studied in the untreated spinal cord of the frog using single or double immunohistochemical stainings. SP and CGRP appear to coexist in the primary afferent fibers and in the marginal and submarginal dorsal horn zones, as well as in the dorsolateral zone. In other parts of the spinal cord CGRP immunoreactivity was scanty while diffuse SP systems were seen, suggesting that the coexistence of the two peptides is restricted to primary afferent fibers.

KW - Calcitonin gene-related peptide

KW - Coexistence

KW - Double method

KW - Frog

KW - Immunohistochemistry

KW - Spinal cord

KW - Substance P

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JO - Neuroscience Letters

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Coexistence of substance P and calcitonin gene-related peptide in the frog spinal cord

Abstract

Keywords

ASJC Scopus subject areas

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