Cloning and sequencing of bovine kidney alkaline phosphatase cDNA

Enrico Garattini; Cheng Hua Jia Cheng Hua; Sidney Udenfriend

doi:10.1016/0378-1119(87)90264-2

Cloning and sequencing of bovine kidney alkaline phosphatase cDNA

Enrico Garattini, Cheng Hua Jia Cheng Hua, Sidney Udenfriend

Istituto di Ricerche Farmacologiche "Mario Negri"

Research output: Contribution to journal › Article › peer-review

Abstract

The molecular cloning and nucleotide sequencing of bovine kidney alkaline phosphatase is reported. The homology with the human enzyme is about 90% at both the nucleotide and amino acid levels. The only significant sequence differences occur at the respective C termini. The high degree of homology also extends into the 5′ and 3′ untranslated regions of the two cDNAs.

Original language	English
Pages (from-to)	41-46
Number of pages	6
Journal	Gene
Volume	59
Issue number	1
DOIs	https://doi.org/10.1016/0378-1119(87)90264-2
Publication status	Published - 1987

Keywords

amino acid sequence
BeWo cell
homology to human enzyme
membrane protein
Recombinant DNA
untranslated region

ASJC Scopus subject areas

Genetics

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10.1016/0378-1119(87)90264-2

Cite this

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title = "Cloning and sequencing of bovine kidney alkaline phosphatase cDNA",

abstract = "The molecular cloning and nucleotide sequencing of bovine kidney alkaline phosphatase is reported. The homology with the human enzyme is about 90% at both the nucleotide and amino acid levels. The only significant sequence differences occur at the respective C termini. The high degree of homology also extends into the 5′ and 3′ untranslated regions of the two cDNAs.",

keywords = "amino acid sequence, BeWo cell, homology to human enzyme, membrane protein, Recombinant DNA, untranslated region",

author = "Enrico Garattini and {Jia Cheng Hua}, {Cheng Hua} and Sidney Udenfriend",

year = "1987",

doi = "10.1016/0378-1119(87)90264-2",

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T1 - Cloning and sequencing of bovine kidney alkaline phosphatase cDNA

AU - Garattini, Enrico

AU - Jia Cheng Hua, Cheng Hua

AU - Udenfriend, Sidney

PY - 1987

Y1 - 1987

N2 - The molecular cloning and nucleotide sequencing of bovine kidney alkaline phosphatase is reported. The homology with the human enzyme is about 90% at both the nucleotide and amino acid levels. The only significant sequence differences occur at the respective C termini. The high degree of homology also extends into the 5′ and 3′ untranslated regions of the two cDNAs.

AB - The molecular cloning and nucleotide sequencing of bovine kidney alkaline phosphatase is reported. The homology with the human enzyme is about 90% at both the nucleotide and amino acid levels. The only significant sequence differences occur at the respective C termini. The high degree of homology also extends into the 5′ and 3′ untranslated regions of the two cDNAs.

KW - amino acid sequence

KW - BeWo cell

KW - homology to human enzyme

KW - membrane protein

KW - Recombinant DNA

KW - untranslated region

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JO - Gene

JF - Gene

IS - 1

ER -

Cloning and sequencing of bovine kidney alkaline phosphatase cDNA

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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