Cloning and developmental expression of AmphiBrn1/2/4, a POU III gene in amphioxus

Simona Candiani, Patrizio Castagnola, Diana Oliveri, Mario Pestarino

Research output: Contribution to journalArticlepeer-review


The large family encoding POU transcription factors has been described in several species. In particular, class III POU genes regulate critical steps of vertebrate and invertebrate neurogenesis. A novel amphioxus class III POU gene, AmphiBrn1/2/4, has been isolated and its spatio-temporal expression has been reported. AmphiBrn1/2/4 is first expressed in the dorsal epiblast, then throughout the neural plate except for a gap at level of the anterior region of the cerebral vesicle. Transcripts are also detected in the primordium of gill slits, pharynx and left Hatschek's diverticulum.

Original languageEnglish
Pages (from-to)231-234
Number of pages4
JournalMechanisms of Development
Issue number1-2
Publication statusPublished - 2002


  • AmphiBrn1/2/4
  • Amphioxus
  • Branchiostoma floridae
  • Developmental expression
  • Endodermic structures
  • Homeodomain
  • Neural tube
  • POU-III class

ASJC Scopus subject areas

  • Developmental Biology
  • Developmental Neuroscience


Dive into the research topics of 'Cloning and developmental expression of AmphiBrn1/2/4, a POU III gene in amphioxus'. Together they form a unique fingerprint.

Cite this