Clinical Parasitology and Parasitome Maps as Old and New Tools to Improve Clinical Microbiomics

Stefania Pane, Maria Vittoria Ristori, Simone Gardini, Alessandra Russo, Federica Del Chierico, Lorenza Putignani

Research output: Contribution to journalReview articlepeer-review


A growing body of evidence shows that dysbiotic gut microbiota may correlate with a wide range of disorders; hence, the clinical use of microbiota maps and fecal microbiota transplantation (FMT) can be exploited in the clinic of some infectious diseases. Through direct or indirect ecological and functional competition, FMT may stimulate decolonization of pathogens or opportunistic pathogens, modulating immune response and colonic inflammation, and restoring intestinal homeostasis, which reduces host damage. Herein, we discuss how diagnostic parasitology may contribute to designing clinical metagenomic pipelines and FMT programs, especially in pediatric subjects. The consequences of more specialized diagnostics in the context of gut microbiota communities may improve the clinical parasitology and extend its applications to the prevention and treatment of several communicable and even noncommunicable disorders.

Original languageEnglish
Issue number12
Publication statusPublished - Nov 28 2021


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