Gestione clinica della gravida con ipotiroidismo - Le azioni

Translated title of the contribution: Clinical management of hypothyroidism in pregnancy - The actions

A. Cassio, L. Chiovato, A. Cicognani, R. M. Dorizzi, Piernicola Garofalo, A. R. Genazzani, D. Glinoer, R. Negro, E. Papini, F. Petraglia, A. Pinchera, M. Tonacchera, V. Toscano, H. Valensise, M. Zini

Research output: Contribution to journalArticlepeer-review


Before pregnancy Diagnosed hypothyodism • Counseling • Increase administration of FT4 or start treatment (goal for TSH: <2.5 mU/L and FT4 within reference limits NO known hypothyroidism • Counseling and estimation of risk • Clinical and biochemical (TSH reflex) assessment and ultrasonography when goiter or nodules are present • Start l-T4 treatment if hypothyroidism is detected Pregnancy • Measure FT4 e TSH and increase l-T4 dose • Involve gynaecologist I - II trimester • Monitor TSH and FT4 bimonthly • Fetal ultrasonography (each trimester) • Thyroid ultrasonography when goiter or nodules are present III trimester • Measure TSH, FT4 and TRAb • Involve paediatrician/neonatologist Delivery • Avoid antisepsis with iodine in newborn and mother • Carry out neonatal screening indicating the mother's disease • Measure TRAb if positive in mother Post-partum Mother: • Decrease l-T4 within one month • Measure FT3, FT4, TSH after 3-9 months Newborn: • Use milk supplemented with iodine • If screening positive involve the pediatrician • Start treatment if TSH increased • In hypothyroidism carry out ultrasonography and measure thyroglobulin and TRAb.

Translated title of the contributionClinical management of hypothyroidism in pregnancy - The actions
Original languageItalian
Pages (from-to)230-231
Number of pages2
JournalRivista Italiana della Medicina di Laboratorio
Issue number4
Publication statusPublished - Oct 2007

ASJC Scopus subject areas

  • Biochemistry, medical
  • Medical Laboratory Technology


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