Aspetti clinici e prognostici nelle epilessie parziali con sintomi uditivi: Confronto tra forme sporadiche e forme familiari

This study aims to determine whether there are important clinical and prognostic differences between sporadic and familial cases of partial epilepsy with auditory symptoms (PEAS) and to define their characteristics. We found 25 patients with PEAS: 9 with a positive family history and 16 sporadic. Onset in the second and third decades of life, recurrent auditory aura followed by generalized seizures, low seizure frequency, benign outcome and scant abnormalities on EEG are the main clinical traits of both sporadic and familial cases that resemble those of the pedigrees reported to date. Differences within our two groups regarding age at onset, seizure frequency under treatment and disease evolution indicate that sporadic cases have a worse, albeit benign, outcome.