Clinical and epidemiological aspects of alzheimer’s disease with presenile onset: A case control study

L. Ferini-Strambi; S. Smirne; P. Garancini; P. Pinto; M. Franceschi

doi:10.1159/000110750

Clinical and epidemiological aspects of alzheimer’s disease with presenile onset: A case control study

L. Ferini-Strambi, S. Smirne, P. Garancini, P. Pinto, M. Franceschi

Research output: Contribution to journal › Article › peer-review

Abstract

Little is known regarding the pathogenetic factors for Alzheimer’s disease (AD). We studied 63 AD patients in order to evaluate if there were clinical subtypes of AD and whether prior illnesses and life-styles were involved in the development of the disease. In our patients selected for onset of symptoms before age 65 we did not find any significant clinical heterogeneity. Furthermore, we found no data in the medical history that are predictive for the development of presenile AD but observed a significantly increased frequency of dementia in the families of AD patients in comparison to controls.

Original language	English
Pages (from-to)	39-49
Number of pages	11
Journal	Neuroepidemiology
Volume	9
Issue number	1
DOIs	https://doi.org/10.1159/000110750
Publication status	Published - 1990

Keywords

Alzheimer’s disease
Case control study
Epidemiology

ASJC Scopus subject areas

Epidemiology
Clinical Neurology

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10.1159/000110750

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AU - Franceschi, M.

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AB - Little is known regarding the pathogenetic factors for Alzheimer’s disease (AD). We studied 63 AD patients in order to evaluate if there were clinical subtypes of AD and whether prior illnesses and life-styles were involved in the development of the disease. In our patients selected for onset of symptoms before age 65 we did not find any significant clinical heterogeneity. Furthermore, we found no data in the medical history that are predictive for the development of presenile AD but observed a significantly increased frequency of dementia in the families of AD patients in comparison to controls.

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Clinical and epidemiological aspects of alzheimer’s disease with presenile onset: A case control study

Abstract

Keywords

ASJC Scopus subject areas

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