Climbing RAS, the everest of oncogenes

Mariangela Russo; Federica Di Nicolantonio; Alberto Bardelli

doi:10.1158/2159-8290.cd-13-0906

Climbing RAS, the everest of oncogenes

Mariangela Russo, Federica Di Nicolantonio, Alberto Bardelli

Istituto Oncologico Candiolo

Research output: Contribution to journal › Article › peer-review

Abstract

Mutations that activate the small GTP-binding protein KRAS are the most common oncogenic event in human tumors. Thirty years after its discovery, mutant KRAS has yet to be therapeutically conquered.

Original language	English
Pages (from-to)	19-21
Number of pages	3
Journal	Cancer Discovery
Volume	4
Issue number	1
DOIs	https://doi.org/10.1158/2159-8290.cd-13-0906
Publication status	Published - Jan 2014

ASJC Scopus subject areas

Oncology

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10.1158/2159-8290.cd-13-0906

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title = "Climbing RAS, the everest of oncogenes",

abstract = "Mutations that activate the small GTP-binding protein KRAS are the most common oncogenic event in human tumors. Thirty years after its discovery, mutant KRAS has yet to be therapeutically conquered.",

author = "Mariangela Russo and {Di Nicolantonio}, Federica and Alberto Bardelli",

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Climbing RAS, the everest of oncogenes

Abstract

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