Abstract
Prolactin has been taken as an index of neuroendocrine function in aging, where dopaminergic neurotransmission in considered to be impaired. The mean concentration of the hormone in the 24 h is higher in the aged men than in the adult controls. A sleep entrained periodicity is present in both aged subjects and controls, but a harmonic analysis of rhythmicity shows that secretory episodes have in aged men a slower periodicity than in adults. In aged men bromocriptine decreases the mean PRL values in the 24 h and the periodicity analysis shows the occurrence of harmonics with shorter period.
Original language | English |
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Pages (from-to) | 317-321 |
Number of pages | 5 |
Journal | Journal of Endocrinological Investigation |
Volume | 4 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1981 |
Keywords
- aging
- bromocriptine
- circadian rhythm
- Prolactin
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism