TY - JOUR
T1 - Cigarette smoking and risk of cerebral sinus thrombosis in oral contraceptive users
T2 - A case-control study
AU - Ciccone, Alfonso
AU - Gatti, A.
AU - Melis, M.
AU - Cossu, G.
AU - Boncoraglio, G.
AU - Carriero, M. R.
AU - Iurlaro, S.
AU - Agostoni, E.
PY - 2005/12
Y1 - 2005/12
N2 - Idiopathic cerebral sinus thrombosis (CST) can cause death and serious neurological disability. It is unknown whether smoking, a major risk factor for arterial stroke, is a risk factor also for CST. This work explored the association between smoking and CST in a hospitalbased, multicentric, case-control study. In order to avoid the confounding effect of the different risk factors for CST, we analysed the homogeneous subgroup of oral contraceptive users. We compared the prevalence of smoking in a group of 43 young women with CST (cases), whose oral contraceptive use was the only known risk factor, with a sample of 255 healthy contraceptive users of similar age (controls). The prevalence of smoking in cases and controls was similar (26% vs. 29%). The age and geographic area-adjusted odds ratio was 0.9; 95% confidence interval, 0.4-1.8; p=0.7. Smoking in oral contraceptive users does not appear to be associated with CST.
AB - Idiopathic cerebral sinus thrombosis (CST) can cause death and serious neurological disability. It is unknown whether smoking, a major risk factor for arterial stroke, is a risk factor also for CST. This work explored the association between smoking and CST in a hospitalbased, multicentric, case-control study. In order to avoid the confounding effect of the different risk factors for CST, we analysed the homogeneous subgroup of oral contraceptive users. We compared the prevalence of smoking in a group of 43 young women with CST (cases), whose oral contraceptive use was the only known risk factor, with a sample of 255 healthy contraceptive users of similar age (controls). The prevalence of smoking in cases and controls was similar (26% vs. 29%). The age and geographic area-adjusted odds ratio was 0.9; 95% confidence interval, 0.4-1.8; p=0.7. Smoking in oral contraceptive users does not appear to be associated with CST.
KW - Case-control studies
KW - Cerebral venous thrombosis
KW - Oral contraceptives
KW - Risk factors
KW - Smoking
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U2 - 10.1007/s10072-005-0507-5
DO - 10.1007/s10072-005-0507-5
M3 - Article
C2 - 16388365
AN - SCOPUS:30744441169
SN - 1590-1874
VL - 26
SP - 319
EP - 323
JO - Neurological Sciences
JF - Neurological Sciences
IS - 5
ER -