Chronic stress reduces the analgesic but not the stimulant effect of morphine in mice

Stefano Puglisi-Allegra; Simona Cabib; Alberto Oliverio

doi:10.1016/0006-8993(86)90234-9

Chronic stress reduces the analgesic but not the stimulant effect of morphine in mice

Stefano Puglisi-Allegra, Simona Cabib, Alberto Oliverio

Fondazione Santa Lucia

Research output: Contribution to journal › Article › peer-review

Abstract

After 10 daily 2-h sessions of immobilization stress, C57BL/6 mice show a reduced response to the analgesic effects of morphine. Chronic stress does not modify the stimulant effect of morphine on locomotor activity. These results are discussed in terms of the effects of stress on different endorphinergic systems.

Original language	English
Pages (from-to)	357-358
Number of pages	2
Journal	Brain Research
Volume	380
Issue number	2
DOIs	https://doi.org/10.1016/0006-8993(86)90234-9
Publication status	Published - Aug 20 1986

Keywords

analgesia
chronic stress
locomotor activity
mice
opioid tolerance

ASJC Scopus subject areas

Developmental Biology
Molecular Biology
Clinical Neurology
Neuroscience(all)

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10.1016/0006-8993(86)90234-9

Cite this

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title = "Chronic stress reduces the analgesic but not the stimulant effect of morphine in mice",

abstract = "After 10 daily 2-h sessions of immobilization stress, C57BL/6 mice show a reduced response to the analgesic effects of morphine. Chronic stress does not modify the stimulant effect of morphine on locomotor activity. These results are discussed in terms of the effects of stress on different endorphinergic systems.",

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author = "Stefano Puglisi-Allegra and Simona Cabib and Alberto Oliverio",

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AU - Puglisi-Allegra, Stefano

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AU - Oliverio, Alberto

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Y1 - 1986/8/20

N2 - After 10 daily 2-h sessions of immobilization stress, C57BL/6 mice show a reduced response to the analgesic effects of morphine. Chronic stress does not modify the stimulant effect of morphine on locomotor activity. These results are discussed in terms of the effects of stress on different endorphinergic systems.

AB - After 10 daily 2-h sessions of immobilization stress, C57BL/6 mice show a reduced response to the analgesic effects of morphine. Chronic stress does not modify the stimulant effect of morphine on locomotor activity. These results are discussed in terms of the effects of stress on different endorphinergic systems.

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KW - chronic stress

KW - locomotor activity

KW - mice

KW - opioid tolerance

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Chronic stress reduces the analgesic but not the stimulant effect of morphine in mice

Abstract

Keywords

ASJC Scopus subject areas

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