Chitosan-coated silica gel as a new support in high-performance liquid chromatography

V. Carunchio; A. M. Girelli; A. Messina; M. Sinibaldi

doi:10.1007/BF02312665

Chitosan-coated silica gel as a new support in high-performance liquid chromatography

V. Carunchio, A. M. Girelli, A. Messina, M. Sinibaldi

Fondazione IRCCS Istituto Nazionale dei Tumori

Research output: Contribution to journal › Article › peer-review

Abstract

A new stationary phase was prepared by immobilizing the chitosan, a natural hydrophilic polymer, on microparticolate silica gel. The effect of the polarity, pH and ionic strength of the mobile phase has been studied in order to find optimal conditions for the separation of nucleotides and aminoacids. The influence of the properties of the mobile phase on the retention was examined, allowing to employ the chitosan-coated silica gel both to anion exchange and adsorption, depending on the pH and the polarity of the eluent used.

Original language	English
Pages (from-to)	731-735
Number of pages	5
Journal	Chromatographia
Volume	23
Issue number	10
DOIs	https://doi.org/10.1007/BF02312665
Publication status	Published - Oct 1987

Keywords

Amino acids
Chitosan-coated silica gel
Column liquid chromatography
Nucleotides

ASJC Scopus subject areas

Analytical Chemistry
Clinical Biochemistry

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10.1007/BF02312665

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abstract = "A new stationary phase was prepared by immobilizing the chitosan, a natural hydrophilic polymer, on microparticolate silica gel. The effect of the polarity, pH and ionic strength of the mobile phase has been studied in order to find optimal conditions for the separation of nucleotides and aminoacids. The influence of the properties of the mobile phase on the retention was examined, allowing to employ the chitosan-coated silica gel both to anion exchange and adsorption, depending on the pH and the polarity of the eluent used.",

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author = "V. Carunchio and Girelli, {A. M.} and A. Messina and M. Sinibaldi",

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AU - Girelli, A. M.

AU - Messina, A.

AU - Sinibaldi, M.

PY - 1987/10

Y1 - 1987/10

N2 - A new stationary phase was prepared by immobilizing the chitosan, a natural hydrophilic polymer, on microparticolate silica gel. The effect of the polarity, pH and ionic strength of the mobile phase has been studied in order to find optimal conditions for the separation of nucleotides and aminoacids. The influence of the properties of the mobile phase on the retention was examined, allowing to employ the chitosan-coated silica gel both to anion exchange and adsorption, depending on the pH and the polarity of the eluent used.

AB - A new stationary phase was prepared by immobilizing the chitosan, a natural hydrophilic polymer, on microparticolate silica gel. The effect of the polarity, pH and ionic strength of the mobile phase has been studied in order to find optimal conditions for the separation of nucleotides and aminoacids. The influence of the properties of the mobile phase on the retention was examined, allowing to employ the chitosan-coated silica gel both to anion exchange and adsorption, depending on the pH and the polarity of the eluent used.

KW - Amino acids

KW - Chitosan-coated silica gel

KW - Column liquid chromatography

KW - Nucleotides

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Chitosan-coated silica gel as a new support in high-performance liquid chromatography

Abstract

Keywords

ASJC Scopus subject areas

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