Characterization of a new TSPY gene family member in Yq (TSPYq1)

A. Ratti; L. Stuppia; V. Gatta; I. Fogh; G. Calabrese; A. Pizzuti; Giandomenico Palka

Characterization of a new TSPY gene family member in Yq (TSPYq1)

A. Ratti, L. Stuppia, V. Gatta, I. Fogh, G. Calabrese, A. Pizzuti, Giandomenico Palka

Fondazione Istituto Auxologico Italiano

Research output: Contribution to journal › Article › peer-review

Abstract

We investigated subinterval 6E on the human Y chromosome, a region frequently deleted in infertile males. YAC yOX17, mapped within subinterval 6E by STS-PCR, was analyzed for the presence of new genes. TSPYq1, a member of the TSPY multi-copy gene family, was isolated and characterized from a yOX17 cosmid subclone. PCR and FISH analysis performed on normal subjects and on patients with microdeletions of Yq suggested the presence of multiple copies of TSPY in Yq. Copyright (C) 2000 S. Karger AG, Basel.

Original language	English
Pages (from-to)	159-162
Number of pages	4
Journal	Cytogenetics and Cell Genetics
Volume	88
Issue number	1-2
Publication status	Published - 2000

ASJC Scopus subject areas

Genetics
Cell Biology

Cite this

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title = "Characterization of a new TSPY gene family member in Yq (TSPYq1)",

abstract = "We investigated subinterval 6E on the human Y chromosome, a region frequently deleted in infertile males. YAC yOX17, mapped within subinterval 6E by STS-PCR, was analyzed for the presence of new genes. TSPYq1, a member of the TSPY multi-copy gene family, was isolated and characterized from a yOX17 cosmid subclone. PCR and FISH analysis performed on normal subjects and on patients with microdeletions of Yq suggested the presence of multiple copies of TSPY in Yq. Copyright (C) 2000 S. Karger AG, Basel.",

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year = "2000",

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journal = "Cytogenetics and Cell Genetics",

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T1 - Characterization of a new TSPY gene family member in Yq (TSPYq1)

AU - Ratti, A.

AU - Stuppia, L.

AU - Gatta, V.

AU - Fogh, I.

AU - Calabrese, G.

AU - Pizzuti, A.

AU - Palka, Giandomenico

PY - 2000

Y1 - 2000

N2 - We investigated subinterval 6E on the human Y chromosome, a region frequently deleted in infertile males. YAC yOX17, mapped within subinterval 6E by STS-PCR, was analyzed for the presence of new genes. TSPYq1, a member of the TSPY multi-copy gene family, was isolated and characterized from a yOX17 cosmid subclone. PCR and FISH analysis performed on normal subjects and on patients with microdeletions of Yq suggested the presence of multiple copies of TSPY in Yq. Copyright (C) 2000 S. Karger AG, Basel.

AB - We investigated subinterval 6E on the human Y chromosome, a region frequently deleted in infertile males. YAC yOX17, mapped within subinterval 6E by STS-PCR, was analyzed for the presence of new genes. TSPYq1, a member of the TSPY multi-copy gene family, was isolated and characterized from a yOX17 cosmid subclone. PCR and FISH analysis performed on normal subjects and on patients with microdeletions of Yq suggested the presence of multiple copies of TSPY in Yq. Copyright (C) 2000 S. Karger AG, Basel.

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M3 - Article

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AN - SCOPUS:0034104036

SN - 0301-0171

VL - 88

SP - 159

EP - 162

JO - Cytogenetics and Cell Genetics

JF - Cytogenetics and Cell Genetics

IS - 1-2

ER -

Characterization of a new TSPY gene family member in Yq (TSPYq1)

Abstract

ASJC Scopus subject areas

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