Changed outcomes of fetuses with congenital heart disease: New Italian multicentre study

Vlasta Fesslova, Jelena Brankovic, Chiara Boschetto, Annaclaudia Masini, Daniela Prandstraller, Antonella Perolo, Flavia Ventriglia, Silvia Macerola, Roberto Crepaz, Cristina Romeo, Francesco De Luca, Agata Previtera, Gabriella Errico

Research output: Contribution to journalArticlepeer-review


Objectives To analyse the outcomes of fetuses with congenital heart disease between 2000 and 2005 in comparison to a previous multicentre study regarding the period 1983-1996. Participants and methods Data of seven centres were prospectively collected, the inclusion criteria being a confirmed fetal diagnosis after birth or at autopsy and a known follow-up, for at least 6 months after birth. Data of 649 fetuses, median age at diagnosis 24 weeks' gestation (15-37), 340/649 (52.4%) diagnosed before 24 weeks, were analysed. Results Sixty seven and 59 cases had chromosomal or extracardiac anomalies (10.3 and 9.1%). Termination of pregnancy was chosen in 21.6% of cases versus 28.9% in the previous study, being significantly lower in cases with early diagnosis (P

Original languageEnglish
Pages (from-to)568-575
Number of pages8
JournalJournal of Cardiovascular Medicine
Issue number8
Publication statusPublished - Aug 1 2015


  • Congenital heart disease
  • Fetal echocardiography
  • Fetus

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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