Abstract
A study was made by in vitro cytotoxic microassay of the cellular immune reaction of patients with different types of tumor against cells from 2 human embryos and 2 fetuses. Peripheral blood lymphocytes from 13 to 19 patients with malignant tumor and 1 of 6 patients with benign tumor showed a killing effect on 1 to 2 mth old embryo cells, whereas no cytotoxicity was demonstrated against 4 to 5 mth old fetal cells and adult skin fibroblasts. These data suggest that patients with malignant tumor are sensitized against antigen(s) in embryo cells.
| Original language | English |
|---|---|
| Pages (from-to) | 667-669 |
| Number of pages | 3 |
| Journal | Journal of the National Cancer Institute |
| Volume | 51 |
| Issue number | 2 |
| Publication status | Published - 1973 |
ASJC Scopus subject areas
- Cancer Research
- Oncology