Abstract
In vitro determination of 3H-thymidine labeling index (LI%) was carried out in craniopharyngiomas from 16 patients submitted to repeated surgical procedures. This study showed a poor correlation between LI% values and prognosis, but allowed to detect a high LI% variation in the same tumor investigated in serial different times. The spatial distribution of S-phase proliferative cells in squamous epithelium of cystic components suggests a rationale for intracavitary treatment of cystic and mixed craniopharingioma and may help explain its success.
| Original language | English |
|---|---|
| Pages (from-to) | 21-23 |
| Number of pages | 3 |
| Journal | Pediatric Neurosurgery |
| Volume | 21 |
| Issue number | SUPPL. 1 |
| Publication status | Published - 1994 |
Keywords
- bleomycin
- cell kinetics
- craniopharyngioma
ASJC Scopus subject areas
- Clinical Neurology
- Pediatrics, Perinatology, and Child Health