Carnitine deficiency: Acute postpartum crisis

C. Angelini, E. Govoni, M. M. Bragaglia, L. Vergani

Research output: Contribution to journalArticlepeer-review


A 16-year-old girl, previously in good health, developed progressive generalized muscle weakness following her first parturition. The neck and proximal limb muscles were especially weak and painful. Carnitine (4-trimethylamino-3-hydroxybutyrate) was markedly decreased in muscle, plasma, and urine. Dietary carnitine supplementation, 2.0 gm daily, was followed by clinical improvement and decreased lipid droplets in muscle biopsy. Together with previously reported cases, 2 fatal, the patient's illness emphasizes the risk of pregnancy in women with carnitine deficiency.

Original languageEnglish
Pages (from-to)558-561
Number of pages4
JournalAnnals of Neurology
Issue number6
Publication statusPublished - 1978

ASJC Scopus subject areas

  • Neuroscience(all)


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