Cardiac Resynchronization Therapy. An Overview on Guidelines

Giuseppe Boriani, Martina Nesti, Matteo Ziacchi, Luigi Padeletti

Research output: Contribution to journalArticlepeer-review


Cardiac resynchronization therapy (CRT) is included in international consensus guidelines as a treatment with proven efficacy in well-selected patients on top of optimal medical therapy. Although all the guidelines strongly recommend CRT for LBBB with QRS duration greater than 150 milliseconds, lower strength of recommendation is reported for QRS duration of 120 to 150 milliseconds, especially if not associated with LBBB. CRT is not recommended for a QRS of less than 120 milliseconds. No indication emerges for guiding the implant based on echocardiographic evaluation of dyssynchrony. Many data indicate that CRT is underused and there is heterogeneity in its implementation.

Original languageEnglish
JournalCardiac Electrophysiology Clinics
Publication statusAccepted/In press - 2015


  • Atrial fibrillation
  • Bundle branch block
  • Cardiac resynchronization therapy
  • Guidelines
  • Heart failure
  • QRS interval

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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