CADASIL: Treatment and Management Options

Anna Bersano; Gloria Bedini; Joshua Oskam; Caterina Mariotti; Franco Taroni; Silvia Baratta; Eugenio Agostino Parati

doi:10.1007/s11940-017-0468-z

CADASIL: Treatment and Management Options

Anna Bersano, Gloria Bedini, Joshua Oskam, Caterina Mariotti, Franco Taroni, Silvia Baratta, Eugenio Agostino Parati

Fondazione IRCCS Istituto Neurologico "C. Besta"

Research output: Contribution to journal › Review article › peer-review

Abstract

CADASIL is a life-threatening and disabling disease. Despite the progress achieved so far, no therapies able to limit the disease progression have been found and only empiric treatments can be employed to relieve the main disease symptoms. Further in vivo studies as well as data aggregation and multi-centre controlled clinical trials are needed to confirm the emerging findings in order to identify evidence-based therapies for CADASIL.

Original language	English
Article number	31
Journal	Current Treatment Options in Neurology
Volume	19
Issue number	9
DOIs	https://doi.org/10.1007/s11940-017-0468-z
Publication status	Published - Sept 1 2017

Keywords

CADASIL
NOTCH3 gene
Pathogenesis
Therapy

ASJC Scopus subject areas

Clinical Neurology

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10.1007/s11940-017-0468-z

Cite this

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title = "CADASIL: Treatment and Management Options",

abstract = "CADASIL is a life-threatening and disabling disease. Despite the progress achieved so far, no therapies able to limit the disease progression have been found and only empiric treatments can be employed to relieve the main disease symptoms. Further in vivo studies as well as data aggregation and multi-centre controlled clinical trials are needed to confirm the emerging findings in order to identify evidence-based therapies for CADASIL.",

keywords = "CADASIL, NOTCH3 gene, Pathogenesis, Therapy",

author = "Anna Bersano and Gloria Bedini and Joshua Oskam and Caterina Mariotti and Franco Taroni and Silvia Baratta and Parati, {Eugenio Agostino}",

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AU - Bersano, Anna

AU - Bedini, Gloria

AU - Oskam, Joshua

AU - Mariotti, Caterina

AU - Taroni, Franco

AU - Baratta, Silvia

AU - Parati, Eugenio Agostino

PY - 2017/9/1

Y1 - 2017/9/1

N2 - CADASIL is a life-threatening and disabling disease. Despite the progress achieved so far, no therapies able to limit the disease progression have been found and only empiric treatments can be employed to relieve the main disease symptoms. Further in vivo studies as well as data aggregation and multi-centre controlled clinical trials are needed to confirm the emerging findings in order to identify evidence-based therapies for CADASIL.

AB - CADASIL is a life-threatening and disabling disease. Despite the progress achieved so far, no therapies able to limit the disease progression have been found and only empiric treatments can be employed to relieve the main disease symptoms. Further in vivo studies as well as data aggregation and multi-centre controlled clinical trials are needed to confirm the emerging findings in order to identify evidence-based therapies for CADASIL.

KW - CADASIL

KW - NOTCH3 gene

KW - Pathogenesis

KW - Therapy

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M1 - 31

ER -

CADASIL: Treatment and Management Options

Abstract

Keywords

ASJC Scopus subject areas

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