TY - JOUR
T1 - Brillouin micro-spectroscopy of subchondral, trabecular bone and articular cartilage of the human femoral head
AU - Cardinali, M A
AU - Dallari, Dante
AU - Govoni, Marco
AU - Stagni, Cesare
AU - Marmi, Federico
AU - Tschon, Matilde
AU - Brogini, Silvia
AU - Fioretto, D
AU - Morresi, A
PY - 2019/4/29
Y1 - 2019/4/29
N2 - Brillouin micro-spectroscopy is applied for investigating the mechanical properties of bone and cartilage tissues of a human femoral head. Distinctive mechanical properties of the cartilage surface, subchondral and trabecular bone are reported, with marked heterogeneities at both micrometric and millimetric length scales. A ubiquitous soft component is reported for the first time, characterized by a longitudinal modulus of about 4.3 GPa, possibly related to the amorphous phase of the bone. This phase is mixed, at micrometric scales, with a harder component, ascribed to mineralized collagen fibrils, characterized by a longitudinal modulus ranging between 16 and 25 GPa.
AB - Brillouin micro-spectroscopy is applied for investigating the mechanical properties of bone and cartilage tissues of a human femoral head. Distinctive mechanical properties of the cartilage surface, subchondral and trabecular bone are reported, with marked heterogeneities at both micrometric and millimetric length scales. A ubiquitous soft component is reported for the first time, characterized by a longitudinal modulus of about 4.3 GPa, possibly related to the amorphous phase of the bone. This phase is mixed, at micrometric scales, with a harder component, ascribed to mineralized collagen fibrils, characterized by a longitudinal modulus ranging between 16 and 25 GPa.
U2 - 10.1364/BOE.10.002606
DO - 10.1364/BOE.10.002606
M3 - Article
C2 - 31143505
SN - 2156-7085
VL - 10
SP - 2606
EP - 2611
JO - Biomedical Optics Express
JF - Biomedical Optics Express
IS - 5
ER -