TY - JOUR
T1 - Breast density assessment using a 3T MRI system
T2 - Comparison among different sequences
AU - Tagliafico, Alberto
AU - Bignotti, Bianca
AU - Tagliafico, Giulio
AU - Astengo, Davide
AU - Martino, Lucia
AU - Airaldi, Sonia
AU - Signori, Alessio
AU - Sormani, Maria Pia
AU - Houssami, Nehmat
AU - Calabrese, Massimo
PY - 2014/6/3
Y1 - 2014/6/3
N2 - Purpose: To compare MRI sequences for breast density measurements on a 3T MRI system using IDEAL (Iterative Decomposition of water and fat with Echo Asymmetry and Least squares estimation) as possible physiology-like reference. Materials and Methods: MRI examination was performed in 48 consecutive patients (mean age 41, years; range, 35-67 years) on a 3.0T scanner and 46 were included. All (fertile) women, were examined between days 5 and 15 of their menstrual cycle. MRI protocol included: T1-turbo spin-echo (T1-tSE), T2-turbo spin-echo (T2-tSE), VIBRANT (Volume Imaging for Breast Assessment) before and after injection of contrast media and IDEAL. Breast density was calculated with semi-automated software. Statistical analysis was performed with non-parametric tests. Results: Mean percentage of breast density calculated in each sequence was: T1-tSE = 56%; T2-tSE = 52%; IDEAL FatOnly = 55%; IDEAL WaterOnly = 53%, VIBRANT = 55%. Significant differences were observed between T2-tSE and both T1-tSE (p
AB - Purpose: To compare MRI sequences for breast density measurements on a 3T MRI system using IDEAL (Iterative Decomposition of water and fat with Echo Asymmetry and Least squares estimation) as possible physiology-like reference. Materials and Methods: MRI examination was performed in 48 consecutive patients (mean age 41, years; range, 35-67 years) on a 3.0T scanner and 46 were included. All (fertile) women, were examined between days 5 and 15 of their menstrual cycle. MRI protocol included: T1-turbo spin-echo (T1-tSE), T2-turbo spin-echo (T2-tSE), VIBRANT (Volume Imaging for Breast Assessment) before and after injection of contrast media and IDEAL. Breast density was calculated with semi-automated software. Statistical analysis was performed with non-parametric tests. Results: Mean percentage of breast density calculated in each sequence was: T1-tSE = 56%; T2-tSE = 52%; IDEAL FatOnly = 55%; IDEAL WaterOnly = 53%, VIBRANT = 55%. Significant differences were observed between T2-tSE and both T1-tSE (p
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U2 - 10.1371/journal.pone.0099027
DO - 10.1371/journal.pone.0099027
M3 - Article
C2 - 24892933
AN - SCOPUS:84902504191
SN - 1932-6203
VL - 9
JO - PLoS One
JF - PLoS One
IS - 6
M1 - e99027
ER -