Brain oxidative metabolism in Parkinson's disease studied by phosphorus 31 magnetic resonance spectroscopy

P. Montagna, G. Pierangeli, P. Cortelli, P. Zaniol, R. Funicello, E. Lugaresi, B. Barbiroli

Research output: Contribution to journalArticlepeer-review

Abstract

Ten patients with Parkinson's disease were studied by phosphorus 31 magnetic resonance spectroscopy. The brain phosphocreatine-inorganic phosphate ratio was abnormal owing to an increased inorganic phosphate content, and the phosphorylation potential was consequently reduced. Phosphocreatine and ADP levels and pH were normal. These findings indicate abnormal brain energy metabolism in Parkinson's disease.

Original languageEnglish
Pages (from-to)225-228
Number of pages4
JournalJournal of Neuroimaging
Volume3
Issue number4
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Neuroscience(all)
  • Radiological and Ultrasound Technology

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