TY - JOUR
T1 - Brain-core temperature of patients before and after orthotopic liver transplantation assessed by DWI thermometry
AU - Sparacia, Gianvincenzo
AU - Cannella, Roberto
AU - Lo Re, Vincenzina
AU - Mamone, Giuseppe
AU - Sakai, Koji
AU - Yamada, Kei
AU - Miraglia, Roberto
PY - 2018/3/19
Y1 - 2018/3/19
N2 - Purpose: To assess brain-core temperature of end-stage liver disease patients undergoing orthotopic liver transplantation (OLT) using a temperature measurement technique based on the apparent diffusion coefficient of the cerebrospinal fluid in the lateral ventricles. Materials and methods: The study group was composed of 19 patients with a model for end-stage liver disease (MELD) score of 23.7 who underwent MR imaging before and after OLT. MR imaging studies were performed with a 1.5T MR scanner. Brain-core temperature (T: °C) was calculated using the following equation from the apparent diffusion coefficient (D) of the cerebrospinal fluid in the lateral ventricles: (Formula presented.) measured with a DWI sequence (b value 1000 s/mm2). We compared brain-core temperature of all patients before and after OLT. Results: Brain-core temperature measurements were successfully taken in all patients before and after OLT. The measured brain-core temperature mean ± standard deviation was 38.67 ± 1.76 °C before OLT and 38.60 ± 0.99 °C after OLT, showing no significant difference (P = 0.643). Conclusions: Brain-core temperature was stable in patients undergoing OLT. DWI thermometry may provide a supplementary brain biomarker to confirm that cerebral blood flow and metabolism are stable in patients undergoing OLT.
AB - Purpose: To assess brain-core temperature of end-stage liver disease patients undergoing orthotopic liver transplantation (OLT) using a temperature measurement technique based on the apparent diffusion coefficient of the cerebrospinal fluid in the lateral ventricles. Materials and methods: The study group was composed of 19 patients with a model for end-stage liver disease (MELD) score of 23.7 who underwent MR imaging before and after OLT. MR imaging studies were performed with a 1.5T MR scanner. Brain-core temperature (T: °C) was calculated using the following equation from the apparent diffusion coefficient (D) of the cerebrospinal fluid in the lateral ventricles: (Formula presented.) measured with a DWI sequence (b value 1000 s/mm2). We compared brain-core temperature of all patients before and after OLT. Results: Brain-core temperature measurements were successfully taken in all patients before and after OLT. The measured brain-core temperature mean ± standard deviation was 38.67 ± 1.76 °C before OLT and 38.60 ± 0.99 °C after OLT, showing no significant difference (P = 0.643). Conclusions: Brain-core temperature was stable in patients undergoing OLT. DWI thermometry may provide a supplementary brain biomarker to confirm that cerebral blood flow and metabolism are stable in patients undergoing OLT.
KW - Diffusion-weighted imaging temperature
KW - DWI thermometry
KW - MR imaging
KW - Orthotopic liver transplantation
KW - Ventricular temperatures
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U2 - 10.1007/s11604-018-0729-0
DO - 10.1007/s11604-018-0729-0
M3 - Article
C2 - 29556899
AN - SCOPUS:85044208572
SN - 1867-1071
SP - 1
EP - 7
JO - Japanese Journal of Radiology
JF - Japanese Journal of Radiology
ER -