BRAF in papillary thyroid carcinoma

Salvatore Giovanni Lanzilotta, Luciano Grammatica, Angelo Paradiso, Gianni Simone

Research output: Contribution to journalArticlepeer-review


Novel genetic findings about papillary thyroid carcinoma identify BRAF gene as a subject of great interest. Involvement of BRAF gene in pathogenesis of PTC, diagnostic value and the putative prognostic significance of its T1799A mutation are summarized in this article. Furthermore, a particular attention is focused to the role of pre-operative detection of BRAF mutation in the FNAB specimens of thyroid nodules and to the use of this gene as target for an effective cancer therapy.

Original languageEnglish
Pages (from-to)269-277
Number of pages9
JournalCellular Oncology
Issue number4
Publication statusPublished - 2007


  • BRAF mutation
  • Fine-needle aspiration
  • Papillary thyroid cancer

ASJC Scopus subject areas

  • Cell Biology
  • Oncology
  • Pathology and Forensic Medicine


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