Biomedical coatings to improve the tissue-biomaterial interface

G. Rizzi, A. Scrivani, M. Fini, Roberto Giardino

Research output: Contribution to journalArticlepeer-review


One of the most important factors determining the degree of tissue interaction of an implanted device is the property of its surface. Thus, great importance is given to chemical and morphological characteristics of biomaterial surfaces to improve biocompatibility, cell migration, proliferation and differentiation, mechanical stability and endogenous tissue ingrowth. In order to obtain new and healing stimulating properties, it is possible to apply a coating or more generally a surface treatment to the surface of a prosthetic device. One of the most versatile methods for coating is thermal spray technology. This paper considers the principle of thermal spray processes and their application in the biomedical field, namely the coatings used for orthopedic prostheses and dental implants. Among thermal spray processes, plasma spray as well as High Velocity Oxygen Fuel (HVOF) processes will be particularly considered and their most important aspects will be illustrated.

Original languageEnglish
Pages (from-to)649-657
Number of pages9
JournalInternational Journal of Artificial Organs
Issue number8
Publication statusPublished - Aug 2004


  • Biomaterial
  • Coatings
  • Prostheses
  • Surfaces
  • Tissue healing

ASJC Scopus subject areas

  • Biophysics


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