TY - JOUR
T1 - Bilateral inguinal hernia with dislocation of great saphenous vein as complication of long-standing granulomatous slack skin
T2 - A case report
AU - Benedetti, M.
AU - Niebel, T.
AU - Tinozzi, F. P.
AU - Vassallo, C.
AU - Brazzelli, V.
AU - Paulli, M.
AU - Borroni, R. G.
AU - Borroni, G.
PY - 2006/5
Y1 - 2006/5
N2 - Granulomatous slack skin (GSS) represents a rare variant of mycosis fungoides, histologically characterized by a variably deep T helper lymphocytes infiltrate with alteration of the dermal elastic tissue and consequent elastolysis, elastophagocytosis and numerous giant cells. Clinically, a development of unelastic, slack skin, especially on flexural areas, is observed. Hereby, we describe a man with a 12-year history of GSS. In 2002, for practical (limitation of movement, deambulation) and cosmetic reasons, he underwent the surgical excision of loose and sagging skinfold over inguinal area, and, afterwards, of the opposite affected inguinal skin. The surgical treatment of bilateral inguinal hernia with reposition of inguinal dislocated vasculature is also reported. In both cases the excised material confirmed the former diagnosis of GSS and revealed a very deep, muscular infiltrate of neoplastic lymphocytes. One year later, a new excision of GSS on the axillae was made. Now, after 2 years, deambulation keeps improving, although an initial relapse of the inguinal slack skin has been observed.
AB - Granulomatous slack skin (GSS) represents a rare variant of mycosis fungoides, histologically characterized by a variably deep T helper lymphocytes infiltrate with alteration of the dermal elastic tissue and consequent elastolysis, elastophagocytosis and numerous giant cells. Clinically, a development of unelastic, slack skin, especially on flexural areas, is observed. Hereby, we describe a man with a 12-year history of GSS. In 2002, for practical (limitation of movement, deambulation) and cosmetic reasons, he underwent the surgical excision of loose and sagging skinfold over inguinal area, and, afterwards, of the opposite affected inguinal skin. The surgical treatment of bilateral inguinal hernia with reposition of inguinal dislocated vasculature is also reported. In both cases the excised material confirmed the former diagnosis of GSS and revealed a very deep, muscular infiltrate of neoplastic lymphocytes. One year later, a new excision of GSS on the axillae was made. Now, after 2 years, deambulation keeps improving, although an initial relapse of the inguinal slack skin has been observed.
KW - Elastolysis
KW - Hernia
KW - Interferon alpha2a
KW - Life style
KW - Mycosis fungoides
KW - Slack skin
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U2 - 10.1111/j.1468-3083.2006.01575.x
DO - 10.1111/j.1468-3083.2006.01575.x
M3 - Article
C2 - 16684291
AN - SCOPUS:33646043130
SN - 0926-9959
VL - 20
SP - 595
EP - 598
JO - Journal of the European Academy of Dermatology and Venereology
JF - Journal of the European Academy of Dermatology and Venereology
IS - 5
ER -