Benign fibrous histiocytoma of bone

F. Bertoni, P. Calderoni, P. Bacchini, A. Sudanese, N. Baldini, D. Present, M. Campanacci

Research output: Contribution to journalArticlepeer-review


The cases of seven patients who had a lytic lesion that was histologically similar to a metaphyseal fibrous defect (non-ossifying fibroma) of bone were studied. The patients all were adults and had pain without a fracture. These findings were considered distinctive for the lesion, which has the same histological appearance as benign fibrous histiocytoma of soft tissue. The lesion is a benign tumor with fibroblastic and histiocytic differentiation. This picture may be seen in foci in other lesions of bone (aneurysmal bone cyst, fibrous dysplasia, and giant-cell tumor). Ten cases of giant-cell tumor of bone that had a large component of the same foci were also reviewed. It should be emphasized that those areas are secondary reactive tissue rather than the true neoplastic tissue of benign fibrous histiocytoma.

Original languageEnglish
Pages (from-to)1225-1230
Number of pages6
JournalJournal of Bone and Joint Surgery - Series A
Issue number8
Publication statusPublished - 1986

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


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