Beneficial effect of fluoxetine in a case of sporadic hyperekplexia

Gianpietro Sechi, Stefano Sotgiu, Maria P. Valenti, Maria G. Pitzolu, Paolo Peterlongo, Lidia Larizza, Giulio Rosati

Research output: Contribution to journalArticlepeer-review


We studied a 67-year-old woman with a sporadic form of hyperekplexia, who experienced 8-10 excessive startle responses to unexpected stimuli per month. Therapy with fluoxetine had a definite beneficial effect. This finding supports the hypothesis that serotonergic mechanisms play a role in this disorder.

Original languageEnglish
Pages (from-to)161-163
Number of pages3
JournalClinical Neuropharmacology
Issue number3
Publication statusPublished - May 2000


  • Fluoxetine
  • Hyperekplexia
  • Serotonergic mechanisms

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Clinical Neurology
  • Neuroscience(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)


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