BCL-6 gene mutations in primary cutaneous B-cell lymphomas

Umberto Gianelli; Amilcare Cerri; Barbara Cassani; Laura Moneghini; Paola Rafaniello Raviele; Emilio Berti; Silvano Bosari

BCL-6 gene mutations in primary cutaneous B-cell lymphomas

Umberto Gianelli, Amilcare Cerri, Barbara Cassani, Laura Moneghini, Paola Rafaniello Raviele, Emilio Berti, Silvano Bosari

Research output: Contribution to journal › Article › peer-review

Abstract

We analyzed mutations in the 5′ non-coding region of the BCL-6 gene in 46 cases of primary cutaneous B-cell lymphomas (PCBCL), using a polymerase chain reaction single strand conformation polymorphism (PCR-SSCP) method. The results indicate that PCBCL display a low frequency of mutations and support a marginal zone B-cell origin for most of these neoplasms.

Original language	English
Pages (from-to)	624-626
Number of pages	3
Journal	Haematologica
Volume	89
Issue number	5
Publication status	Published - May 2004

Keywords

BCL-6 gene
BCL-6 mutations
Cutaneous lymphoma
Extranodal non-Hodgkin's lymphoma
Primary cutaneous B-cell lymphomas

ASJC Scopus subject areas

Hematology

Cite this

@article{bd1d068ff54b46e29f931f4804a7175a,

title = "BCL-6 gene mutations in primary cutaneous B-cell lymphomas",

abstract = "We analyzed mutations in the 5′ non-coding region of the BCL-6 gene in 46 cases of primary cutaneous B-cell lymphomas (PCBCL), using a polymerase chain reaction single strand conformation polymorphism (PCR-SSCP) method. The results indicate that PCBCL display a low frequency of mutations and support a marginal zone B-cell origin for most of these neoplasms.",

keywords = "BCL-6 gene, BCL-6 mutations, Cutaneous lymphoma, Extranodal non-Hodgkin's lymphoma, Primary cutaneous B-cell lymphomas",

author = "Umberto Gianelli and Amilcare Cerri and Barbara Cassani and Laura Moneghini and Raviele, {Paola Rafaniello} and Emilio Berti and Silvano Bosari",

year = "2004",

month = may,

language = "English",

volume = "89",

pages = "624--626",

journal = "Haematologica",

issn = "0390-6078",

publisher = "NLM (Medline)",

number = "5",

}

TY - JOUR

T1 - BCL-6 gene mutations in primary cutaneous B-cell lymphomas

AU - Gianelli, Umberto

AU - Cerri, Amilcare

AU - Cassani, Barbara

AU - Moneghini, Laura

AU - Raviele, Paola Rafaniello

AU - Berti, Emilio

AU - Bosari, Silvano

PY - 2004/5

Y1 - 2004/5

N2 - We analyzed mutations in the 5′ non-coding region of the BCL-6 gene in 46 cases of primary cutaneous B-cell lymphomas (PCBCL), using a polymerase chain reaction single strand conformation polymorphism (PCR-SSCP) method. The results indicate that PCBCL display a low frequency of mutations and support a marginal zone B-cell origin for most of these neoplasms.

AB - We analyzed mutations in the 5′ non-coding region of the BCL-6 gene in 46 cases of primary cutaneous B-cell lymphomas (PCBCL), using a polymerase chain reaction single strand conformation polymorphism (PCR-SSCP) method. The results indicate that PCBCL display a low frequency of mutations and support a marginal zone B-cell origin for most of these neoplasms.

KW - BCL-6 gene

KW - BCL-6 mutations

KW - Cutaneous lymphoma

KW - Extranodal non-Hodgkin's lymphoma

KW - Primary cutaneous B-cell lymphomas

UR - http://www.scopus.com/inward/record.url?scp=2542479950&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=2542479950&partnerID=8YFLogxK

M3 - Article

C2 - 15136235

AN - SCOPUS:2542479950

SN - 0390-6078

VL - 89

SP - 624

EP - 626

JO - Haematologica

JF - Haematologica

IS - 5

ER -

BCL-6 gene mutations in primary cutaneous B-cell lymphomas

Abstract

Keywords

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this