BCL-6 gene mutations in primary cutaneous B-cell lymphomas

Umberto Gianelli, Amilcare Cerri, Barbara Cassani, Laura Moneghini, Paola Rafaniello Raviele, Emilio Berti, Silvano Bosari

Research output: Contribution to journalArticlepeer-review


We analyzed mutations in the 5′ non-coding region of the BCL-6 gene in 46 cases of primary cutaneous B-cell lymphomas (PCBCL), using a polymerase chain reaction single strand conformation polymorphism (PCR-SSCP) method. The results indicate that PCBCL display a low frequency of mutations and support a marginal zone B-cell origin for most of these neoplasms.

Original languageEnglish
Pages (from-to)624-626
Number of pages3
Issue number5
Publication statusPublished - May 2004


  • BCL-6 gene
  • BCL-6 mutations
  • Cutaneous lymphoma
  • Extranodal non-Hodgkin's lymphoma
  • Primary cutaneous B-cell lymphomas

ASJC Scopus subject areas

  • Hematology


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