Availability of hyperacetylated H4 histone in intact nucleosomes to specific antibodies

U. Pfeffer, N. Ferrari, G. Vidali

Research output: Contribution to journalArticlepeer-review

Abstract

Specific antibodies against the tetra-acetylated form of H4 histone have been elicited in the rabbit. They do not cross-react with the non-, mono-, and di-acetylated forms of the histone molecule but a slight cross-reactivity with the tri-acetylated form of H4 histone is observed. Our studies also show that hyperacetylated H4 histones are recognized by the antibodies in intact nucleosomes.

Original languageEnglish
Pages (from-to)2496-2498
Number of pages3
JournalJournal of Biological Chemistry
Volume261
Issue number6
Publication statusPublished - 1986

ASJC Scopus subject areas

  • Biochemistry

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