TY - JOUR
T1 - Automatic Pleural Line Extraction and COVID-19 Scoring from Lung Ultrasound Data
AU - Carrer, Leonardo
AU - Donini, Elena
AU - Marinelli, Daniele
AU - Zanetti, Massimo
AU - Mento, Federico
AU - Torri, Elena
AU - Smargiassi, Andrea
AU - Inchingolo, Riccardo
AU - Soldati, Gino
AU - Demi, Libertario
AU - Bovolo, Francesca
AU - Bruzzone, Lorenzo
N1 - Funding Information:
Manuscript received April 30, 2020; accepted June 23, 2020. Date of publication June 29, 2020; date of current version October 26, 2020. This work was supported by the VRT Foundation for this research (COVID-19 Call 2020) under Grant #1. (Corresponding author: Lorenzo Bruzzone.) Leonardo Carrer, Daniele Marinelli, Federico Mento, Libertario Demi, and Lorenzo Bruzzone are with the Department of Information Engineering and Computer Science, University of Trento, 38123 Trento, Italy (e-mail: lorenzo.bruzzone. . nitn.it).
Publisher Copyright:
© 1986-2012 IEEE.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/11
Y1 - 2020/11
N2 - Recent works highlighted the significant potential of lung ultrasound (LUS) imaging in the management of subjects affected by COVID-19. In general, the development of objective, fast, and accurate automatic methods for LUS data evaluation is still at an early stage. This is particularly true for COVID-19 diagnostic. In this article, we propose an automatic and unsupervised method for the detection and localization of the pleural line in LUS data based on the hidden Markov model and Viterbi Algorithm. The pleural line localization step is followed by a supervised classification procedure based on the support vector machine (SVM). The classifier evaluates the healthiness level of a patient and, if present, the severity of the pathology, i.e., the score value for each image of a given LUS acquisition. The experiments performed on a variety of LUS data acquired in Italian hospitals with both linear and convex probes highlight the effectiveness of the proposed method. The average overall accuracy in detecting the pleura is 84% and 94% for convex and linear probes, respectively. The accuracy of the SVM classification in correctly evaluating the severity of COVID-19 related pleural line alterations is about 88% and 94% for convex and linear probes, respectively. The results as well as the visualization of the detected pleural line and the predicted score chart, provide a significant support to medical staff for further evaluating the patient condition.
AB - Recent works highlighted the significant potential of lung ultrasound (LUS) imaging in the management of subjects affected by COVID-19. In general, the development of objective, fast, and accurate automatic methods for LUS data evaluation is still at an early stage. This is particularly true for COVID-19 diagnostic. In this article, we propose an automatic and unsupervised method for the detection and localization of the pleural line in LUS data based on the hidden Markov model and Viterbi Algorithm. The pleural line localization step is followed by a supervised classification procedure based on the support vector machine (SVM). The classifier evaluates the healthiness level of a patient and, if present, the severity of the pathology, i.e., the score value for each image of a given LUS acquisition. The experiments performed on a variety of LUS data acquired in Italian hospitals with both linear and convex probes highlight the effectiveness of the proposed method. The average overall accuracy in detecting the pleura is 84% and 94% for convex and linear probes, respectively. The accuracy of the SVM classification in correctly evaluating the severity of COVID-19 related pleural line alterations is about 88% and 94% for convex and linear probes, respectively. The results as well as the visualization of the detected pleural line and the predicted score chart, provide a significant support to medical staff for further evaluating the patient condition.
KW - COVID-19
KW - diagnostic
KW - lung ultrasound (LUS) imaging
KW - signal processing
KW - support vector machine (SVM)
KW - Viterbi algorithm
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U2 - 10.1109/TUFFC.2020.3005512
DO - 10.1109/TUFFC.2020.3005512
M3 - Article
C2 - 32746195
AN - SCOPUS:85093959523
SN - 0885-3010
VL - 67
SP - 2207
EP - 2217
JO - IRE Transactions on Ultrasonic Engineering
JF - IRE Transactions on Ultrasonic Engineering
IS - 11
M1 - 9127515
ER -