Atypical/dysplastic nevi

Giovanni Pellacani, Francesca Farnetani, Giuseppe Argenziano, Iris Zalaudek, Caterina Longo, Melissa Gill

Research output: Chapter in Book/Report/Conference proceedingChapter


Atypical nevi, also referred as dysplastic nevi, are characterized by intermediate aspects in between to common nevi and melanomas. From a clinical point of view, they usually show up as larger and more irregular and nonhomogenously pigmented lesions than common nevi. In dermatopathology, they are classically characterized by lentiginous melanocytic hyperplasia, epithelioid melanocytic atypia, lamellar fibroplasias and perivascular lymphocytic infiltrate [1]. From these observations a pathogenetic model for stepwise development of a MM from a nevus has been proposed. However, this model remains controversial due to nonclear and reproducible clinical definition of dysplastic nevus, limitations in recognition of early melanoma and dysplastic nevus, and weak correlation between histologic dysplasia and clinical atypia [2].

Original languageEnglish
Title of host publicationReflectance Confocal Microscopy for Skin Diseases
PublisherSpringer Berlin Heidelberg
Number of pages12
ISBN (Print)9783642219979, 9783642219962
Publication statusPublished - Jan 1 2012

ASJC Scopus subject areas

  • Medicine(all)


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