Atypical/dysplastic nevi

Giovanni Pellacani; Francesca Farnetani; Giuseppe Argenziano; Iris Zalaudek; Caterina Longo; Melissa Gill

doi:10.1007/978-3-642-21997-9_9

Atypical/dysplastic nevi

Giovanni Pellacani, Francesca Farnetani, Giuseppe Argenziano, Iris Zalaudek, Caterina Longo, Melissa Gill

Arcispedale Santa Maria Nuova

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Atypical nevi, also referred as dysplastic nevi, are characterized by intermediate aspects in between to common nevi and melanomas. From a clinical point of view, they usually show up as larger and more irregular and nonhomogenously pigmented lesions than common nevi. In dermatopathology, they are classically characterized by lentiginous melanocytic hyperplasia, epithelioid melanocytic atypia, lamellar fibroplasias and perivascular lymphocytic infiltrate [1]. From these observations a pathogenetic model for stepwise development of a MM from a nevus has been proposed. However, this model remains controversial due to nonclear and reproducible clinical definition of dysplastic nevus, limitations in recognition of early melanoma and dysplastic nevus, and weak correlation between histologic dysplasia and clinical atypia [2].

Original language	English
Title of host publication	Reflectance Confocal Microscopy for Skin Diseases
Publisher	Springer Berlin Heidelberg
Pages	87-98
Number of pages	12
ISBN (Print)	9783642219979, 9783642219962
DOIs	https://doi.org/10.1007/978-3-642-21997-9_9
Publication status	Published - Jan 1 2012

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-3-642-21997-9_9

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AU - Pellacani, Giovanni

AU - Farnetani, Francesca

AU - Argenziano, Giuseppe

AU - Zalaudek, Iris

AU - Longo, Caterina

AU - Gill, Melissa

PY - 2012/1/1

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Atypical/dysplastic nevi

Abstract

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