Atypical presentation of plasma cell leukemia secondary to multiple myeloma detected by F-18 FDG PET/CT

Fabrizio Cocciolillo, Giorgio Treglia, Maria Felicia Villani, Alessandro Giordano

Research output: Contribution to journalArticlepeer-review

Abstract

We report a case of atypical muscle localization of plasma cell leukemia (PCL), arisen from a secondary leukemic transformation of multiple myeloma (MM), detected by F-18 FDG PET/CT. A 57-year-old woman with a history of MM received chemotherapy and hematopoietic stem cell transplantation with complete treatment response. Five years later, the patient presented a recurrence of MM and an evolution in PCL. F-18 FDG PET/CT showed areas of increased radiopharmaceutical uptake in some muscles of the right leg and right thigh, corresponding to muscle localization of PCL, therefore allowing adequate treatment planning.

Original languageEnglish
JournalClinical Nuclear Medicine
Volume36
Issue number12
DOIs
Publication statusPublished - Dec 2011

Keywords

  • F-18 FDG
  • multiple myeloma
  • PET/CT
  • plasma cell leukemia

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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