Association of a wide invasive malignant thymoma with myastenia gravis and primary hyperparathyroidism due to parathyroid adenoma: Case report and review of the literature

Vincenzo Triggiani; Edoardo Guastamacchia; Ivan Lolli; Giuseppe Troccoli; Francesco Resta; Carlo Sabbà; Nadia Ruggieri; Emilio Tafaro

doi:10.1080/08923970600809587

Association of a wide invasive malignant thymoma with myastenia gravis and primary hyperparathyroidism due to parathyroid adenoma: Case report and review of the literature

Vincenzo Triggiani, Edoardo Guastamacchia, Ivan Lolli, Giuseppe Troccoli, Francesco Resta, Carlo Sabbà, Nadia Ruggieri, Emilio Tafaro

Ente Ospedaliero Specializzato in Gastroenterologia "Saverio de Bellis"

Research output: Contribution to journal › Article › peer-review

Abstract

There are few cases described in the world literature reporting an association of thymoma (with myasthenia gravis or not) with hyperparathyroidism. In these cases the hyperparathyroidism was due to the presence of an adenoma or hyperplasic parathyroid tissue either in the cervical region or in an ectopic intrathymic location.(12345) In other cases the syndrome of hypercalcemia was due to the secretion of parathyroid-related protein (PTHRP) (6) or parathyroid hormone (PTH) (7) by the thymoma itself. We report the first case, at the best of our knowledge, of a wide invasive malignant thymoma (type B3), associated with myasthenia gravis and hyperparathyroidism caused by parathyroid adenoma.

Original language	English
Pages (from-to)	377-385
Number of pages	9
Journal	Immunopharmacology and Immunotoxicology
Volume	28
Issue number	2
DOIs	https://doi.org/10.1080/08923970600809587
Publication status	Published - Jul 1 2006

ASJC Scopus subject areas

Immunology
Pharmacology
Toxicology
Health, Toxicology and Mutagenesis

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10.1080/08923970600809587

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Triggiani, V., Guastamacchia, E., Lolli, I., Troccoli, G., Resta, F., Sabbà, C., Ruggieri, N., & Tafaro, E. (2006). Association of a wide invasive malignant thymoma with myastenia gravis and primary hyperparathyroidism due to parathyroid adenoma: Case report and review of the literature. Immunopharmacology and Immunotoxicology, 28(2), 377-385. https://doi.org/10.1080/08923970600809587

Association of a wide invasive malignant thymoma with myastenia gravis and primary hyperparathyroidism due to parathyroid adenoma : Case report and review of the literature. / Triggiani, Vincenzo; Guastamacchia, Edoardo; Lolli, Ivan et al.

In: Immunopharmacology and Immunotoxicology, Vol. 28, No. 2, 01.07.2006, p. 377-385.

Research output: Contribution to journal › Article › peer-review

Triggiani, V, Guastamacchia, E, Lolli, I, Troccoli, G, Resta, F, Sabbà, C, Ruggieri, N & Tafaro, E 2006, 'Association of a wide invasive malignant thymoma with myastenia gravis and primary hyperparathyroidism due to parathyroid adenoma: Case report and review of the literature', Immunopharmacology and Immunotoxicology, vol. 28, no. 2, pp. 377-385. https://doi.org/10.1080/08923970600809587

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abstract = "There are few cases described in the world literature reporting an association of thymoma (with myasthenia gravis or not) with hyperparathyroidism. In these cases the hyperparathyroidism was due to the presence of an adenoma or hyperplasic parathyroid tissue either in the cervical region or in an ectopic intrathymic location.(12345) In other cases the syndrome of hypercalcemia was due to the secretion of parathyroid-related protein (PTHRP) (6) or parathyroid hormone (PTH) (7) by the thymoma itself. We report the first case, at the best of our knowledge, of a wide invasive malignant thymoma (type B3), associated with myasthenia gravis and hyperparathyroidism caused by parathyroid adenoma.",

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AU - Troccoli, Giuseppe

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AU - Sabbà, Carlo

AU - Ruggieri, Nadia

AU - Tafaro, Emilio

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Association of a wide invasive malignant thymoma with myastenia gravis and primary hyperparathyroidism due to parathyroid adenoma: Case report and review of the literature

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