TY - JOUR
T1 - Assignment of human teratocarcinoma derived growth factor (TDGF) sequences to chromosomes 2q37, 3q22, 6p25 and 19q13.1
AU - Scognamiglio, B.
AU - Baldassarre, G.
AU - Cassano, C.
AU - Tucci, M.
AU - Montuori, N.
AU - Dono, R.
AU - Lembo, G.
AU - Barra, A.
AU - Lago, C. T.
AU - Viglietto, G.
AU - Rocchi, M.
AU - Persico, M. Graziella
PY - 1999
Y1 - 1999
N2 - The human teratocarcinoma derived growth factor 1 (TDGF1) gene maps on chromosome (Chr) 3p21.3. One pseudogene (TDGF3) maps on Chr Xq21→q22. We now report the nucleotide sequence and chromosome location of three additional TDGF pseudogenes. The three new sequences (TDGF2, TDGF4 and TDGF5) are truncated at the 5' end and have accumulated several point mutations, deletions and insertions. TDGF2, TDGF4 and TDGF6 map on Chrs 2q37, 6p25 and 3q22, respectively. Finally, Southern blot analysis of DNA from normal individuals shows a highly variable restriction pattern of the TDGF sequences.
AB - The human teratocarcinoma derived growth factor 1 (TDGF1) gene maps on chromosome (Chr) 3p21.3. One pseudogene (TDGF3) maps on Chr Xq21→q22. We now report the nucleotide sequence and chromosome location of three additional TDGF pseudogenes. The three new sequences (TDGF2, TDGF4 and TDGF5) are truncated at the 5' end and have accumulated several point mutations, deletions and insertions. TDGF2, TDGF4 and TDGF6 map on Chrs 2q37, 6p25 and 3q22, respectively. Finally, Southern blot analysis of DNA from normal individuals shows a highly variable restriction pattern of the TDGF sequences.
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M3 - Article
C2 - 10393436
AN - SCOPUS:0033019351
SN - 0301-0171
VL - 84
SP - 220
EP - 224
JO - Cytogenetics and Cell Genetics
JF - Cytogenetics and Cell Genetics
IS - 3-4
ER -