Antiepileptic Drugs and Brain Tumor Patients

Leslie Ray, Marta Maschio, Herbert B. Newton

Research output: Chapter in Book/Report/Conference proceedingChapter


Epilepsy is a common complication of patients with primary and metastatic brain tumors. To date, there has been no significant reduction in seizure frequency with the use of prophylactic antiepileptic drugs (AEDs), except for use as surgical prophylaxis. However, once brain tumor-related epilepsy (BTRE) has been established, optimal treatment remains unknown. In addition, despite adequate therapeutic concentrations of AEDs, refractory seizures are often common. In this chapter, we will review the evidence for various AEDs in the context of brain tumor-related epilepsy (BTRE).

Original languageEnglish
Title of host publicationEpilepsy and Brain Tumors
PublisherElsevier Inc.
Number of pages11
ISBN (Print)9780124171268, 9780124170438
Publication statusPublished - Mar 4 2015


  • Brain tumor-related epilepsy
  • Lacosamide
  • Levetiracetam
  • Oxcarbazepine
  • Pregabilin
  • Topiramate

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)


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