Anterior uveitis complicating zoledronic acid infusion

Annalisa Colucci; Giulio Modorati; Elisabetta Miserocchi; Federico Di Matteo; Paolo Rama

doi:10.1080/09273940902916111

Anterior uveitis complicating zoledronic acid infusion

Annalisa Colucci, Giulio Modorati, Elisabetta Miserocchi, Federico Di Matteo, Paolo Rama

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Zoledronic acid is the most effective treatment in patients with hypercalcemia secondary to malignancy; occasionally it can be related to ocular inflammation. We report a case of severe unilateral anterior uveitis following administration of intravenous zoledronic acid in a patient with frontal hyperostosis secondary to breast cancer. The patient developed anterior uveitis 24 hours after the administration of intravenous zoledronate. The patient was treated with topical prednisone and cycloplegic eye drops, with complete recovery after one month. This report shows that, on rare occasions, zoledronic acid can be a possible cause of acute anterior uveitis. Copyright Informa Healthcare 2009.

Original language	English
Pages (from-to)	267-268
Number of pages	2
Journal	Ocular Immunology and Inflammation
Volume	17
Issue number	4
DOIs	https://doi.org/10.1080/09273940902916111
Publication status	Published - Aug 2009

Keywords

Bisphosphonates
Breast cancer
Uveitis
Zoledronate

ASJC Scopus subject areas

Ophthalmology
Immunology and Allergy

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10.1080/09273940902916111

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title = "Anterior uveitis complicating zoledronic acid infusion",

abstract = "Zoledronic acid is the most effective treatment in patients with hypercalcemia secondary to malignancy; occasionally it can be related to ocular inflammation. We report a case of severe unilateral anterior uveitis following administration of intravenous zoledronic acid in a patient with frontal hyperostosis secondary to breast cancer. The patient developed anterior uveitis 24 hours after the administration of intravenous zoledronate. The patient was treated with topical prednisone and cycloplegic eye drops, with complete recovery after one month. This report shows that, on rare occasions, zoledronic acid can be a possible cause of acute anterior uveitis. Copyright Informa Healthcare 2009.",

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AU - Colucci, Annalisa

AU - Modorati, Giulio

AU - Miserocchi, Elisabetta

AU - Di Matteo, Federico

AU - Rama, Paolo

PY - 2009/8

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N2 - Zoledronic acid is the most effective treatment in patients with hypercalcemia secondary to malignancy; occasionally it can be related to ocular inflammation. We report a case of severe unilateral anterior uveitis following administration of intravenous zoledronic acid in a patient with frontal hyperostosis secondary to breast cancer. The patient developed anterior uveitis 24 hours after the administration of intravenous zoledronate. The patient was treated with topical prednisone and cycloplegic eye drops, with complete recovery after one month. This report shows that, on rare occasions, zoledronic acid can be a possible cause of acute anterior uveitis. Copyright Informa Healthcare 2009.

AB - Zoledronic acid is the most effective treatment in patients with hypercalcemia secondary to malignancy; occasionally it can be related to ocular inflammation. We report a case of severe unilateral anterior uveitis following administration of intravenous zoledronic acid in a patient with frontal hyperostosis secondary to breast cancer. The patient developed anterior uveitis 24 hours after the administration of intravenous zoledronate. The patient was treated with topical prednisone and cycloplegic eye drops, with complete recovery after one month. This report shows that, on rare occasions, zoledronic acid can be a possible cause of acute anterior uveitis. Copyright Informa Healthcare 2009.

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KW - Uveitis

KW - Zoledronate

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Anterior uveitis complicating zoledronic acid infusion

Abstract

Keywords

ASJC Scopus subject areas

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