TY - JOUR
T1 - An automatic classification technique for attenuation correction in positron emission tomography
AU - Bettinardi, V.
AU - Pagani, E.
AU - Gilardi, M. C.
AU - Landoni, C.
AU - Riddell, C.
AU - Rizzo, G.
AU - Castiglioni, I.
AU - Belluzzo, D.
AU - Lucignani, G.
AU - Schubert, S.
AU - Fazio, F.
PY - 1999
Y1 - 1999
N2 - In this paper a clustering technique is proposed for attenuation correction (AC) in positron emission tomography (PET). The method is unsupervised and adaptive with respect to counting statistics in the transmission (TR) images. The technique allows the classification of pre- or post-injection TR images into main tissue components in terms of attenuation coefficients. The classified TR images are then forward projected to generate new TR sinograms to be used for AC in the reconstruction of the corresponding emission (EM) data. The technique has been tested on phantoms and clinical data of brain, heart and whole-body PET studies. The method allows: (a) reduction of noise propagation from TR into EM images, (b) reduction of TR scanning to a few minutes (3 min) with maintenance of the quantitative accuracy (within 6%) of longer acquisition scans (15-20 min), (c) reduction of the radiation dose to the patient, (d) performance of quantitative whole-body studies.
AB - In this paper a clustering technique is proposed for attenuation correction (AC) in positron emission tomography (PET). The method is unsupervised and adaptive with respect to counting statistics in the transmission (TR) images. The technique allows the classification of pre- or post-injection TR images into main tissue components in terms of attenuation coefficients. The classified TR images are then forward projected to generate new TR sinograms to be used for AC in the reconstruction of the corresponding emission (EM) data. The technique has been tested on phantoms and clinical data of brain, heart and whole-body PET studies. The method allows: (a) reduction of noise propagation from TR into EM images, (b) reduction of TR scanning to a few minutes (3 min) with maintenance of the quantitative accuracy (within 6%) of longer acquisition scans (15-20 min), (c) reduction of the radiation dose to the patient, (d) performance of quantitative whole-body studies.
KW - Attenuation correction
KW - Clustering technique
KW - Position emission tomography
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U2 - 10.1007/s002590050410
DO - 10.1007/s002590050410
M3 - Article
C2 - 10382087
AN - SCOPUS:0011954972
SN - 0340-6199
VL - 26
SP - 447
EP - 458
JO - European Journal of Pediatrics
JF - European Journal of Pediatrics
IS - 5
ER -