Acute myelitis and ChAdOx1 nCoV-19 vaccine: Casual or causal association?

Research output: Contribution to journalArticlepeer-review


A 44-year-old previously healthy woman developed acute myelitis in close temporal relationship with ChAdOx1 nCoV-19 vaccine first-dose administration. The neurological involvement was mainly sensory with neuroimaging showing two mono-metameric lesions involving the posterior and lateral cord at dorsal level. Significant improvement was promptly recorded with high-dose intravenous steroids, with complete recovery within one month. The strict temporal relationship between vaccination and myelitis, together with the absence of clues pointing to alternative diagnoses, might suggest a conceivable role for anti-SARS-CoV-2 vaccine as immunological trigger, although a causal relationship has yet to be established and our preliminary observation suggests caution.

Original languageEnglish
Pages (from-to)577686
JournalJournal of Neuroimmunology
Publication statusE-pub ahead of print - Jul 31 2021


Dive into the research topics of 'Acute myelitis and ChAdOx1 nCoV-19 vaccine: Casual or causal association?'. Together they form a unique fingerprint.

Cite this