Acute coronary syndrome without coronary obstructions: Diagnosis and treatment

Giampaolo Niccoli, Giancarla Scalone, Filippo Crea

Research output: Contribution to journalArticlepeer-review


>Myocardial infarction with no obstructive coronary atherosclerosis (MINOCA) is a syndrome with different causes. Its prevalence ranges between 5% and 25% of all myocardial infarctions. The prognosis is extremely variable, as it strictly depends on the cause of MINOCA. Clinical history, electrocardiography, cardiac enzymes, echocardiography, coronary angiography, and left ventricular angiography represent first-level diagnostic investigations to identify the causes of MINOCA. This preliminary step helps divide patients presenting with epicardial or microvascular patterns and to perform specific additional tests for an adequate management workflow. This article will focus on the diagnosis and treatment of MINOCA.

Original languageEnglish
Pages (from-to)9-14
Number of pages6
JournalHeart and Metabolism
Issue number75
Publication statusPublished - Jan 1 2018


  • Acute myocardial infarction
  • Microcirculation
  • No obstructive coronary atherosclerosis

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine


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