A Therapeutic and Diagnostic Multidisciplinary Pathway for Merkel Cell Carcinoma Patients

Marco Rastrelli, Paolo Del Fiore, Alessandra Buja, Antonella Vecchiato, Carlo Riccardo Rossi, Vanna Chiarion Sileni, Saveria Tropea, Francesco Russano, Manuel Zorzi, Romina Spina, Rocco Cappellesso, Renzo Mazzarotto, Francesco Cavallin, Franco Bassetto, Elisabetta Bezzon, Beatrice Ferrazzi, Mauro Alaibac, Simone Mocellin

Research output: Contribution to journalArticlepeer-review


Merkel Cell Carcinoma (MCC) is a highly aggressive neuroendocrine neoplasm of the skin. Due to its rarity, the management of MCC is not standardized across centers. In this article, we present the experience of the Veneto region in the North-East of Italy, where a committee of skin cancer experts has proposed a clinical pathway for the diagnosis and treatment of MCC. Putting together the evidence available in the international literature, we outlined the best approach to the management of patients affected with this malignancy step- by- step for each possible clinical situation. Crucial in this pathway is the role of the multidisciplinary team to deal with the lack of robust information on each aspect of the management of this disease.

Original languageEnglish
Article number529
Number of pages8
JournalFrontiers in Oncology
Publication statusPublished - Apr 15 2020


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