A single nucleotide polymorphism in SLC1A1 gene is associated with age of onset of obsessive-compulsive disorder

S. Dallaspezia; M. Mazza; C. Lorenzi; F. Benedetti; E. Smeraldi

doi:10.1016/j.eurpsy.2014.02.006

A single nucleotide polymorphism in SLC1A1 gene is associated with age of onset of obsessive-compulsive disorder

S. Dallaspezia, M. Mazza, C. Lorenzi, F. Benedetti, E. Smeraldi

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Different genetic polymorphisms in the SLC1A1 have been shown to be associated with obsessive-compulsive disorder. Rs301430 is a T/C functional polymorphism affecting the gene expression and extrasynaptic glutamate concentration.We observed that Rs301430 influence age at onset in obsessive-compulsive disorder.

Original language	English
Pages (from-to)	301-303
Number of pages	3
Journal	European Psychiatry
Volume	29
Issue number	5
DOIs	https://doi.org/10.1016/j.eurpsy.2014.02.006
Publication status	Published - 2014

Keywords

Age at onset
Glutamate
Obsessive-compulsive disorder
Rs301430
SLC1A1

ASJC Scopus subject areas

Psychiatry and Mental health
Medicine(all)

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10.1016/j.eurpsy.2014.02.006

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abstract = "Different genetic polymorphisms in the SLC1A1 have been shown to be associated with obsessive-compulsive disorder. Rs301430 is a T/C functional polymorphism affecting the gene expression and extrasynaptic glutamate concentration.We observed that Rs301430 influence age at onset in obsessive-compulsive disorder.",

keywords = "Age at onset, Glutamate, Obsessive-compulsive disorder, Rs301430, SLC1A1",

author = "S. Dallaspezia and M. Mazza and C. Lorenzi and F. Benedetti and E. Smeraldi",

year = "2014",

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AU - Mazza, M.

AU - Lorenzi, C.

AU - Benedetti, F.

AU - Smeraldi, E.

PY - 2014

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AB - Different genetic polymorphisms in the SLC1A1 have been shown to be associated with obsessive-compulsive disorder. Rs301430 is a T/C functional polymorphism affecting the gene expression and extrasynaptic glutamate concentration.We observed that Rs301430 influence age at onset in obsessive-compulsive disorder.

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KW - Glutamate

KW - Obsessive-compulsive disorder

KW - Rs301430

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A single nucleotide polymorphism in SLC1A1 gene is associated with age of onset of obsessive-compulsive disorder

Abstract

Keywords

ASJC Scopus subject areas

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