A nonrigid registration of MR breast images using complex-valued wavelet transform

L. Mainardi, K. M. Passera, A. Lucesoli, D. Vergnaghi, G. Trecate, E. Setti, R. Musumeci, S. Cerutti

Research output: Contribution to journalArticlepeer-review


In this paper, a fast, slice-by-slice, nonrigid registration algorithm of dynamic magnetic resonance breast images is presented. The method is based on a multiresolution motion estimation of the breast using complex discrete wavelet transform (CDWT): the pyramid of oriented complex subimages is used to implement a hierarchical phase-matching-based motion estimation algorithm. The resulting motion estimate is nonrigid and pixel-independent. To assess the method performance, we computed the correlation coefficient and the normalized mutual information between pre- and postcontrast images with and without realignment. The indices increased after using our approach and the improvement was superior to rigid or affine registration. A set of clinical scores was also evaluated. The clinical validation demonstrated an increased readability in the subtraction images. In particular, CDWT registration allowed a best definition of breast and lesion borders and greater detail detectability.

Original languageEnglish
Pages (from-to)27-36
Number of pages10
JournalJournal of Digital Imaging
Issue number1
Publication statusPublished - Mar 2008


  • Breast
  • Contrast agent
  • Magnetic resonance
  • Nonrigid
  • Registration algorithm
  • Wavelet transform

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Computer Vision and Pattern Recognition


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