A mysterious case of gastroparesis: could the secret be found in a drink?

Mariabeatrice Principi, Ranaldo Nunzio, Giuseppe Ingravallo, Giuseppe Riezzo, Elisabetta Damiani, Antonio Ferrannini, Roberta Rossi, Leonardo Resta, Enzo Ierardi, Alfredo Di Leo

Research output: Contribution to journalArticlepeer-review


Gastroparesis is a disorder characterized by delayed gastric emptying of a meal in the absence of a mechanical gastric outlet obstruction. Idiopathic gastroparesis is at least as common as diabetic gastroparesis in most case series, and the true prevalence of gastroparesis is unknown. We report here an interesting case of idiopathic gastroparesis characterized by sudden onset in a female patient. The diagnosis was confirmed by ultrasonographic study of gastric emptying and electrogastrography, by gastric endoscopy/histology, and finally by allergy tests. The disorder was found to be due to a rare cause, namely an allergic predisposition. In fact, our patient, who demonstrated an allergy to gold salts, had drunk a glass of a liqueur containing gold flakes and developed an eosinophilic aggregation in the gastric mucosa observed at gastric endoscopy/histology. The symptoms disappeared after steroid administration. Our experience suggests that gastric histology and close enquiry into any history of allergy may be useful diagnostic tools in cases of idiopathic gastroparesis.

Original languageEnglish
Pages (from-to)187-189
Number of pages3
JournalInflammation and Allergy - Drug Targets
Issue number3
Publication statusPublished - Jun 2013

ASJC Scopus subject areas

  • Medicine(all)


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